Centellian24: The Korean Skincare Brand Built on Centella Science
A derma-cosmetic line from Dongkook Pharmaceutical that channels 50+ years of pharmaceutical research into Centella Asiatica-powered skincare.
Centellian24 is a Korean skincare brand from Dongkook Pharmaceutical, a Seoul-based pharmaceutical company founded in 1968. Its range is built largely around TECA — a concentrated, standardized Centella Asiatica extract — and it is best known for its Madeca line of barrier-focused creams and high-potency brightening ampoules. On Kayty, the brand is represented by its Expert Madeca Mela Capture Ampoule Max.
Who This Brand Is For
If you are dealing with a compromised skin barrier, early signs of aging, or stubborn post-sun dark spots, Centellian24 is worth your attention. This is a Korean skincare brand that sits firmly in the derma-cosmetics space: ingredient-led, formulation-serious, and built around one plant extract that the brand says is refined to pharmaceutical standards. It appeals to people who want the reassurance of scientific rigor behind their serum or cream — particularly those with sensitive or reactive skin who need actives that do not destabilize the barrier while they work.
Where the Brand Comes From
Dongkook Pharmaceutical, established in 1968, entered the cosmetics market in 2015 with the launch of the derma-cosmetic brand Centellian24, based on the core ingredient TECA (Titrated Extract of Centella Asiatica), leveraging Dongkook's expertise in developing plant-based raw materials. The parent company had spent decades developing pharmaceutical-grade wound-care and dermatology products before it ever formulated a cream — which is an unusual origin for a skincare brand and a meaningful one. Centellian24 was born from Dongkook Pharmaceutical's 50 years of research and development expertise, and the brand says it has maintained a leading position in the derma-cosmetic category.
The name itself signals the intent. The brand's core value is to provide dermatological solutions based on skin science technology, and it was born on the basis of delivering powerful skin science solutions that maintain efficacy around the clock, anchored in Centella Asiatica extraction technology — TECA.
What Centellian24 Is Known For
The brand's signature is TECA. While many Korean brands include a percentage of Centella Asiatica extract for its soothing properties, Centellian24 says it works from a pharmaceutical-grade standardized extract that isolates and concentrates the plant's four active triterpenoids. According to the brand, its flagship Madeca Cream features TECA to help support the skin barrier, and the company sources Centella leaves from Madagascar and refines them through a seven-step extraction process.
According to the brand, only 2% is extracted from 100kg of Centella Asiatica, which gives a sense of just how concentrated the finished ingredient is compared with a standard plant extract. The Madeca line grew from this single point of difference. Madeca Cream, based on the company's proprietary ingredient TECA, became a sensation, selling out on home shopping channels after launch, and the brand has since expanded that foundation into serums, ampoules, and eye treatments — all built on the same TECA core. According to the brand, its core product, Madeca Cream, has sold a total of 78 million units since its launch in 2015.
More recently, the Madeca line has extended into brightening territory — pairing TECA's barrier-supportive properties with high-concentration pigmentation actives. In May 2026, Centellian24 launched at 1,400 Ulta stores with its hero product Madeca Cream Time Reverse, formulated with 12 Centella extracts and Active-TECA to address concerns including lines, wrinkles, firmness, uneven tone, and dullness.
