
Anua PDRN Hyaluronic Acid Capsule 100 Serum: What It Is, What's Inside, and Who It's For
A fast-absorbing hydrating serum that combines multiple forms of hyaluronic acid, Sodium DNA, and hydrolyzed collagen in what the brand calls a microcapsule delivery system.
The Anua PDRN Hyaluronic Acid Capsule 100 Serum is a lightweight daily hydration serum positioned for all skin types, including sensitive skin. It layers multiple forms of hyaluronic acid with Sodium DNA and hydrolyzed collagen, in a microcapsule system the brand says absorbs faster than traditional liposomes, for a dewy, non-heavy finish.
Who This Serum Is For
If your main concern is hydration — whether your skin feels tight after cleansing or looks dull by midday — the Anua PDRN Hyaluronic Acid Capsule 100 Serum is built with a broad enough formula to suit you. It is listed as suitable for all skin types, which in practice means it works whether your skin leans dry, oily, combination, or sensitive.
If you are pregnant, breastfeeding, recovering from a procedure or using prescription skincare, check the brand's current guidance and ask your doctor before adding it. Also keep in mind: the PDRN (Sodium DNA) here is derived from salmon, so skip it if you have a fish sensitivity. As always, a patch test is still recommended the first time you use it.
What It Is and How It Feels
At its core, this is a hydration serum — specifically, one designed to address moisture at multiple levels of the skin. The texture is a true serum liquid: fluid enough to spread easily but not watery to the point of running. It absorbs quickly, which means you are not left waiting between steps, and it leaves a dewy finish rather than a matte or tacky one.
The microcapsule delivery system is what sets this apart from a standard hyaluronic acid serum. The brand describes its capsule technology as faster-absorbing than traditional liposomes, designed to help hydration absorb rather than sit on top of the skin. For a hydration serum, the delivery method matters as much as the ingredients themselves.
The Ingredients That Matter
The brand describes the formula as built on 11 types of hyaluronic acid. The ingredient list includes both Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate — two forms that work at different molecular sizes. Hydrolyzed Hyaluronic Acid is broken down to a smaller size, which allows it to reach deeper layers, while Sodium Hyaluronate works closer to the surface to bind moisture and reduce water loss.
Sodium DNA (PDRN) is the ingredient that gives the serum its name. It is a polynucleotide that is included here as a skin-supporting active in the hydration context.
Hydrolyzed Collagen appears as a key ingredient. In a serum formula, it functions to support the skin's texture and help retain moisture rather than physically replacing collagen.
Glutathione is included and is well known in Korean skincare for its role in supporting an even, luminous complexion. Its presence here adds a brightening dimension to what is primarily a hydration-focused serum.
Niacinamide also appears in the full ingredient list. It is a widely used multitasking ingredient that works with the hydration core of this formula without pulling the serum in a separate direction.
How to Use It and Where It Goes in a Routine
The usage instructions are simple: apply a few drops to the face and gently pat in with your fingertips. You use it both morning and night, and it goes on before your moisturizer. In a full routine, that means it follows your toner or essence and precedes anything heavier.

